Associate Scientist, In-vivo Pharmacology
Who are we?
Recent advances in T-cell engineering and antibody therapeutics have led to phenomenal results in treating cancer patients, opening the possibility for combining these powerful therapeutic modalities. Unum Therapeutics aims to transform cancer treatment through the discovery, development, and commercialization of novel cellular immunotherapies. We’re moving forward fast, are you? Visit www.unumrx.com for our latest news!
What are we offering to you?
This is an outstanding opportunity to join a well-funded startup company early in its trajectory. You will be a vital part of helping to achieve the Unum vision: to transform cancer treatment and deliver patient cures. Unum is a place where your input matters. You will have a direct and significant impact on our in-vivo studies as well as taking a significant role in overseeing our animal facility operations. You will also shape the Unum culture and be a part of a passionate, transparent, and collaborative work environment.
This is a great opportunity for an acadmic veterinary technician or in-vivo facilities operations associate with dosing experience to transition into industry with the possibility of a temp-to perm conversion of this six-month contract role (not guaranteed, but certainly possible).
What will you be doing?
We are seeking a talented and dedicated Associate Scientist who is interested in joining a highly dynamic, smart, and fun team of in-vivo pharmacology scientists developing a cutting-edge cellular platform for cancer patients across both hematologic and solid tumor malignancies.
This individual will have the opportunity to actively participate in decision-making on scientific direction for programs and will have exposure to a variety of stages of drug discovery and development. We are seeking individuals who hold themselves to a high bar in terms of results, self-motivation, resiliency, and applying learning to stretch and grow as a professional.
The successful candidate will possess hands-on experience in designing, performing, and interpreting in vivo studies using laboratory mice, dosing and collection of a variety of tissues and organs after euthanasia. In addition, ideally s/he will be also have proven experience with a variety of ex-vivo sample processing and analysis techniques, including preparation of samples for flow cytometry and immunohistochemistry as well as additional immunology and cell-based assays (e.g. FACS, cytokine, cell culture, etc.).
- In partnership with Senior Scientists within the in-vivo pharmacology team, design, plan, execute and interpret in-vivo studies utilizing a variety of techniques including dosing (IV, SC, IP), tumor measurements, blood and tissue collection, necropsies, and IVIS imaging
- Analysis and presentation of in-vivo study data, providing scientific interpretations and recommendations in both team and company settings
- Planning and coordination of experiments with team members and facility operations
- Seeking ways to improve workflows, execution, and processes within the in-vivo pharmacology group
- Understanding and compliance with IACUC protocols and regulations involved with in-vivo work
- Ensuring appropriate EH&S compliance within both vivarium and laboratory settings
- Maintaining accurate and well-organized records and laboratory notebook
- Supporting development of protocols, study reports and data presentations
Critical Success Factors
- Strong scientific curiosity, willingness to rapidly learn new laboratory and data analysis methods, and ability to apply learning from experiences
- Highly organized with strong analytical skills and attentive to detail
- Self-starter with strong problem-solving abilities, resourcefulness, and an outstanding team player with ability to work in groups as well as independently
- Effective interpersonal skills and a strong communication skillset with the ability to clearly present study objectives, data and conclusions
- Ability to multitask, prioritize, and function in a fast-paced, entrepreneurial environment
Who are we seeking?
- BS/BA or MS/MA in a scientific discipline with 3-8 years of industry/academic experience with in-vivo studies
- Strong in-vivo pharmacology background, including proficiency in dosing via a variety of routes (IV, IP, SC), aseptic technique, and harvesting and processing of biological samples for ex vivo analysis
- Experience with models of oncology in immunocompromised mice, tumor volume measurement, IVIS imaging and graphing software (Excel, Prism) is a plus
- Experience with tissue culture, flow cytometry or ELISA is a plus
For more information on the position or to apply, check out their job posting.